The Lubbock Fire Department arrived after a call of a structure fire. The woman, Alisha Loftis and her son Gianni Pollard were rescued from the house and taken to the University Medical Center, but were later pronounced dead.
Neighbors in the area said they saw the house on fire and went over to help. Shanna Roe says she could hear the boy screaming from inside.
"When I went over there to call her name, I didn't hear her but the little boy was saying, 'Help me.' It blew the windows out and everything and it took them a minute to get to them and by the time they did they were already suffocated from the smoke I'm sure. It was just awful."
The Fire Marshall's office says the woman's two other children were notified while in school Tuesday. The cause of the fire is still under investigation.